Etomidate as an induction agent for endotracheal intubation in patients with sepsis.

نویسنده

  • Manoj K Mittal
چکیده

Opposing authors provide succinct, authoritative discussions of controversial issues in emergency medicine. Authors are provided the opportunity to review and comment on opposing presentations. Each topic is accompanied by an Editor’s Note that summarizes important concepts. Participation as an authoritative discussant is by invitation only, but suggestions for topics and potential authors can be submitted to the section editors

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Etomidate, sepsis, and adrenal function: not as bad as we thought?

The choice of induction agent for endotracheal intubation can have significant downstream effects, especially in critically ill patients. In a retrospective study, Ray and McKeown found that the choice of induction agent had no significant effect on use of vasoactive medications, corticosteroids, or mortality. Given the heated debate regarding corticosteroids in septic shock and the role that e...

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CLINICAL CONTROVERSIES Clinical Controversies: Etomidate as an Induction Agent for Endotracheal Intubation in Patients With Sepsis

Opposing authors provide succinct, authoritative discussions of controversial issues in emergency medicine. Authors are provided the opportunity to review and comment on opposing presentations. Each topic is accompanied by an Editor’s Note that summarizes important concepts. Participation as an authoritative discussant is by invitation only, but suggestions for topics and potential authors can ...

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The Effect of Single-Bolus Etomidate on Septic Patient Mortality: A Retrospective Review

BACKGROUND Because of its many desirable properties, etomidate is widely used as an induction agent for endotracheal intubation. However, some have recently called into question the safety of etomidate for even single-bolus use due to its known effects on adrenal suppression. OBJECTIVES We sought to compare the in-hospital mortality between septic patients given etomidate and those given alte...

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Etomidate for intubation of patients who have sepsis or septic shock - where do we go from here?

Etomidate is an intravenous induction agent that is associated with hemodynamic stability during intubation. The agent is therefore attractive for use in critically ill patients who have a high risk of hemodynamic instability during this procedure. However, etomidate causes adrenal suppression, which itself has been associated with increased mortality in critically ill patients. The ongoing deb...

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Ketamine and Propofol Combination (“Ketofol”) for Endotracheal Intubations in Critically Ill Patients: A Case Series

BACKGROUND Endotracheal intubation is a common procedure performed for critically ill patients that can have immediate life-threatening complications. Induction medications are routinely given to facilitate the procedure, but most of these medications are associated with hypotension. While etomidate is known for its neutral hemodynamic profile, it has been linked with increased mortality in sep...

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عنوان ژورنال:
  • Annals of emergency medicine

دوره 53 3  شماره 

صفحات  -

تاریخ انتشار 2009